Jimmy Garoppolo threw two touchdown passes and the San Francisco 49ers stayed away en route to a resounding 31-10 victory over the Los Angeles Rams on Monday night in Santa Clara, California.
Deebo Samuel caught a touchdown pass and rushed to score another and George Kittle added a touchdown reception as San Francisco (4-5) held the ball for 39 minutes and three seconds. Jimmie Ward had two interceptions and returned one for a touchdown as the 49ers beat the NFC West rivals Rams for the fifth time in a row.
Matthew Stafford completed 26 of 41 passes for 243 yards, a touchdown and two interceptions for Los Angeles (7-3), which lost its second straight game. Tyler Higbee caught a touchdown pass for the Rams.
Odell Beckham Jr. caught two passes for 18 yards while playing sparingly in his first game since joining the Rams. Cooper Kupp equaled his season record of 11 receptions, good for 122 yards.
Garoppolo completed 15 of 19 passes for 182 yards and San Francisco won at home for the first time in five attempts this season. Los Angeles fell to 4-1 on the road.
The 49ers outscored the Rams 335 yards to 278 while winning for the second time in their last seven games. Samuel had five receptions for 97 yards and rushed five times for 36 yards, and Elijah Mitchell gained 91 yards on 27 carries.
San Francisco quickly set the tone after Ward took his first pick from Stafford with just 2:03 left.
The 49ers possessed the ball for 11:03 while driving 93 yards on 18 plays. San Francisco ran the ball 13 times and Garoppolo made 5 of 5 passes, including an 8-yard touchdown pass to Kittle with 1:54 left in the fourth.
Just 65 seconds later, the 49ers had a 14-0 lead. Higbee couldn’t catch Stafford’s short pass and the ball approached Ward, who returned the pick 27 yards for a touchdown.
Los Angeles got on the board with 13:16 left at the half when Stafford threw a 10-yard touchdown pass to Higbee. The 49ers responded with another marathon excursion, and Samuel scored on an 8-yard dash to cap a 91-yard, 11-play drive that took 7:52.
San Francisco increased its lead to 24-7 on a 50-yard field goal by Robbie Gould with 4:38 remaining in the third quarter. The 49ers ended the game in the fourth quarter when Garoppolo joined Samuel on a 40-yard touchdown on fourth-and-6 to make it 31-7 with 11:07 left.
The Rams’ Matt Gay kicked a 37-yard field goal with 3:48 left.