Research Team Finds Ways To Use Opioids For More Effective Pain Management – Saskatoon | The Canadian News

A research team from across Canada is investigating how natural opiates are produced and how they can be used for more effective pain management.

Pain relievers are known to cause many side effects and carry the potential for addiction.

The research team is focusing on an enzyme it found at the Canadian Light Source facility at the University of Saskatchewan (USask).


Click to Play Video: 'USask Research Projects Aim to Address the Issues of the COVID-19 Pandemic'



USask Research Projects Aim to Address the Issues of the COVID-19 Pandemic


USask Research Projects Aim to Address the Issues of the COVID-19 Pandemic

It is part of the process of creating codeine and comes from the poppy.

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University of Calgary PhD student Samuel Carr highlighted the importance of a machine in the Canadian light source that produces different types of light to study materials at the molecular level.

“It is really critical. We can’t do this job without him synchrotron“Carr said.” Without it, it would be impossible to image the enzyme. “

University of Windsor professor Ken Ng says opioids such as morphine and codeine provide relief for many patients, from the pain they feel after mild surgery to the chronic pain that cancer patients experience. However, this type of medication can cause multiple side effects and can lead to physical dependence with long-term use. Improving pain relievers would help millions of people have a better quality of life.

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Carr says these are the initial steps to hopefully someday provide an effective means of creating a pain reliever with fewer side effects.

“Think of this as an assembly line,” Carr said. “There are many different steps in this specific pathway, and each enzyme contributes a different step from the initial product to the finished drug.

“We would need to modify the enzyme to advance our research and the process of reaching our end goal.”

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Reference-globalnews.ca

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