Moderna’s vaccine is more likely to cause heart inflammation than Pfizer’s: study

Moderna’s Covid-19 vaccine is up to four times more likely to cause heart muscle inflammation, a very rare side effect, than its rival in Pfizer and BioNTech according to a Danish study published in the British Medical Journal.

The study, involving 4.9 million people over the age of 12, or nearly 85% of Danes, investigated the relationship between Covid-19 vaccines based on mRNA and inflammation of the heart, also known as myocarditis The miopericarditis.

Previous studies in Israel and the United States indicated an increased risk of inflammation of the heart after inoculation with the mRNA vaccines developed by Pfizer-BioNTech and Modern.

“Vaccination with mRNA-1273 (Moderna’s vaccine) was associated with a significantly increased risk of myocarditis or myopericarditis in the Danish population,” the study notes.

However, the overall risk of developing a inflammation of the heart Because of the vaccines, both based on mRNA technology, it was low, according to the study, conducted by researchers at the Statens Serum Institute in Denmark.

“In general, the rate of myocarditis or myopericarditis was three to four times higher in the case of the mRNA-1273 vaccine (Modern) than in the BNT162b2 vaccine (Pfizer-BioNTech), “says the study.

The researchers found only 1 case per 71,400 vaccinated with Pfizer-BioNTech and 1 case for every 23,800 vaccinated with Moderna. Most of the cases were mild, according to the study.

The Pfizer-BioNTech vaccine it was only associated with a greater risk of heart inflammation among womenaccording to the study, which contrasts with the results of the studies from Israel and the United States.

The authors said the discrepancy could be explained by the mean age of the vaccinated population, the time span between the first and second injections, or because fewer Danes had tested positive for Covid-19.

“Our findings do not overall overshadow the many benefits that vaccination brings,” study author Anders Hviid said in a statement.

“It must be taken into account that the alternative of contracting a Covid-19 infection it probably also carries a risk of inflammation in the heart muscle, “Hviid said.

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