Moderna says that trials of its childhood vaccine against Covid-19 were a success


American biotech company modern said this Wednesday that he will ask for the approval of his Covid-19 vaccine in children six months to five years after trials showed it to be safe and generate a strong immune response.

Two 25 microgram doses given to children in this age group produced antibody levels similar to the levels achieved by two 100 microgram doses in 18 to 25 year olds.

Based on these data, modern said that in the coming weeks it will submit applications for authorization to the United States Drug Agency (FDA), the European Medicines Agency (EMA) and other regulators.

The results “are good news for parents of children under the age of six,” Moderna CEO Stephane Bancel said in a statement. “We now have clinical data on the performance of our vaccine from children as young as six months to older adults.”

The company, however, registered a relatively low efficacy of the vaccine with respect to infections in their trials, which were carried out during the wave of the omicron variant.

The effectiveness of the vaccine in children from six months to two years was 43.7%, and 37.5% in those from two to five years.

Moderna, which stated that these levels are similar to those seen in adults, is evaluating a third dose to increase them.

The trial involved 11,700 children in the United States and Canada, 4,200 of them between the ages of two and six years and 2,500 between the ages of six months and two years.

Moderna added that, after consultation with the FDA, it will also seek approval for two 50-microgram doses in children ages 6 to 11, and will update its application for approval for adolescents ages 12 to 17.

The EMA and other regulators have already authorized Moderna’s vaccine in these groups.

Last month, the FDA postponed its debates on the license of the vaccine of PfizerBioNTech for children under five years of age, arguing that it needed additional data on the third dose. The companies said they expect that data to be ready by April.



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